John Frangos Awarded National Institutes of Health Grant on Vascular Mechanotransduction

Grant Award from National Institutes of Health to John A Frangos. Shear Stress Activation of Endothelial Membrane Function $2,137,500

ABOUT THIS PROJECT

Atherosclerosis occurs at regions of the vasculature where blood flow is highly unsteady and oscillatory, suggesting that this blood flow pattern promotes the disease. This project will determine how this blood flow pattern induces the signals that lead to atherosclerosis. If successful, it will provide a basis for drug design for its treatment.